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Red flags that warrant a rheumatology referral: Prolonged morning stiffness (over 3060 minutes), symmetric small-joint involvement, soft-tissue swelling rather than bony enlargement, systemic symptoms, or OA presenting at an unusually young age or in atypical joints

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Frequently Asked Questions How long does it take to feel semaglutide's effects after my first injection

The deal includes potential milestone payments of up to $660 million and tiered royalties on sales

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