glp 1 and heart failure GLP-1RA in Different HFpEF Phenotypes GLP-1RAs reduce cardiovascular deaths in

Results l-carnitine displayed a protective effect against synovitis of KOA in vitro and in vivo experiments

However, further investigations are needed to validate the above hypothesis

Figure 14 Statements Author contributions All authors listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication

Findlay VJ

Administration of CBP or LDH inhibitors, or cell-penetrating peptides that can specifically block the lactylation of MRE11, can reduce the lactylation of MRE11, inhibit HR, and enhance the sensitivity of tumor cells to chemotherapeutic agents such as cisplatin, PARPi, etc [26]

Lundgren JD, Baraniuk JN, Ostrowski NL, Kaliner MA, Shelhamer JH