In a phase 2b trial, tirzepatide treatment was associated in a dose-dependent manner with decreased levels of apolipoprotein (apo) B, apoC-III, large triglyceride-rich lipoprotein particles, and small low-density lipoprotein particles, suggesting a shift towards a less atherogenic lipoprotein profile [77]
Full-text review was subsequently performed, with approximately 20 to 35 studies informing the final narrative synthesis
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MCE, HY-106376) and trolox (Sigma-Aldrich, 238813) were diluted in water at 100 mM and added at the indicated concentrations
Matched buccal swabs served as germline controls