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2 MASLD is primarily characterized by abnormal lipid accumulation in hepatocytes, typically presenting as simple steatosis
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10.1007/s00726-007-0582-4 39
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Integration of autosomal dominant AD patient CSF proteomics with brain tissue pathology identified SMOC1 as being abnormally elevated in the CSF nearly 30 years before the onset of cognitive symptoms, marking it as the earliest known biomarker of AD [200, 201]
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