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Key Industry Developments: In October 2025 , Eli Lilly and Company achieved its fourth Phase III success with its oral GLP-1 receptor agonist, orforglipron, in type 2 diabetes trials

With the recent confirmation of the therapeutic role of GLP-1RA in MASLD, a broader dosage spectrum is needed to respond to individualized treatments with different metabolic profiles

SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM Trial Committees and Investigators

Lancet Diabetes Endocrinol