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Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting

Orforglipron binds as a small synthetic molecule to the GLP-1 receptor and activates the downstream signaling cascade, which in research is associated with delayed gastric emptying, satiety signals, and effects on glucose homeostasis

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Here, they are utilised as fuel, indicating its significant role in the body's energy production

Rapoport, B., Chazenbalk, G

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