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Tirzepatide, a GLP-1/GIP dual agonist, has demonstrated mean body weight reductions of approximately 20.9% over 72 weeks in adults with obesity

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Imtiaz said human observational studies have found a link between lower MOTs-C levels and components of metabolic syndrome, like obesity and insulin resistance, but there have been no patient trials with the peptide

Due to polymorphisms, gene duplication, and genetic recombination, GSTs have multiple isoenzymes with overlapping substrate specificity and diversity [200]