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Unlike BCTC, exendin 939 also mitigated both thermal and mechanical nociceptive behaviors in mice without inducing hyperthermia, indicating that it is a viable analgesic without the common adverse effects associated with existing pain management strategies, such as opioids and traditional TRPV1 antagonists 32,42,51,52,53

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By targeting these receptors, tirzepatide suppresses appetite and delays stomach emptying, which reduces food intake