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The most chemically complex of all the vitamins, methylcobalamin is a water-soluble, organometallic compound with a trivalent cobalt ion bound inside a corrin ring which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded
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Its possible that they overdid it with their supplements, or that their bodies naturally absorb more of these vitamins or metabolize them more slowly, Fallin told ResearchGate
B12 absorption depends on a protein produced in your stomach called intrinsic factor
Children presenting neurological signs or symptoms, those unable to take oral medication, individuals with known malabsorption syndromes, infants under 6 months old, and patients using medications that may interfere with vitamin B12 absorption are typically treated with a parenteral protocol (1)