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4 Others: GIPR/GLP-1R dual agonists and GIPR/GLP-1R/GCGR triagonists Intestinal endocrine K cells produce gastric inhibitory polypeptide (GIP)

Microdosing may sound like a clever hack, but Defnet says it comes with real risks: Short answer: Not without talking to a health care professional first

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Figure 28: Photograph of the gastrointestinal researchers at Bispebjerg Hospital in 1975, credit: Figure 1.3.3, Holst 2024

Barry says

Additionally, the secondary bile acids 3-oxoLCA and isoLCA function as TGR5 agonists that suppress the differentiation of Th17 cells in vitro through two mechanisms: (1) directly inhibiting the expression of RORt, and (2) promoting the polarization of M2 macrophages, which indirectly inhibits the development of Th17 cells (119)