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Adverse Event Reporting and Safety Monitoring FDA-approved medications exist within a comprehensive pharmacovigilance system

10.1038/sj.ki.5000089 7 BatraG.LakicG

Common in vitro dosing ranges from 10 to 100 ng/mL, adjusted per cell type and endpoint

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Deficiency of GSH, the major intracellular thiol, has been shown in human patients with acute pancreatitis, HIV infection, hyperthyroidism, Type I diabetes, and cirrhosis, 3-6 and has been associated with disease severity and decreased survival in some studies

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