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This has prompted multiple studies investigating the perioperative use of NAC to prevent postoperative pulmonary complications in various surgical settings, though no meta-analyses exist within the literature specific to pulmonary outcomes

DPP-4's S 2 pocket accommodates a wide range of lipophilic rings, with only a slight decrease in effectiveness for very small three-membered or large twelve-membered rings

10.1038/s42255-022-00591-z [DOI] [PMC free article] [PubMed] [Google Scholar] Nair P, Bindhu O, Mussavira S (2025) Biomarkers approved: the life cycle of drug development

If prescribed, domperidone should only be used at the lowest effective dose for up to 7 days due to cardiac risks (QT prolongation), and is contraindicated in patients with certain cardiac conditions or taking interacting medications

The role of kinetic context in apparent biased agonism at GPCRs