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ABSTRACT: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual glucose-dependent insulinotropic polypeptide/GLP-1 RAs are common therapies for managing diabetes and obesity, but gastrointestinal (GI) adverse effects (AEs) such as nausea, vomiting, diarrhea, and constipation frequently limit therapy

Also, keep in mind that while one medication may be more effective on paper, the best option for you will depend on your lifestyle, medical history, and insurance coverage

Contrave (naltrexone/bupropion) and Wegovy (semaglutide) are brand-name medications prescribed to help certain adults lose weight and keep it off

Whether the drugs can be used to prevent or treat dementia is also being studied, with mixed results

International Journal of Molecular Sciences, 24 (2), 1703

People who use opioid medications cannot take Contrave safely