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Description

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Exendin-4 (and later its synthetic version, exenatide) acted upon cells in the pancreas to increase insulin production

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Likewise, administration of encapsulated bitter compounds derived from Gentiana lutea root with a standardized breakfast reduced total daily energy intake by ~20% in healthy individuals (60), while oral insensitivity to the bitter taste of 6-n-propylthrouracil was associated with increased energy intake in female subjects (72)

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