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Binding-Site Purification of Actives (B-SPA) enables efficient large-scale progression of fragment hits by combining multi-step array synthesis with HT Crystallography

Pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and vascular endothelial growth factor (VEGF), play pivotal roles in orchestrating retinal inflammation

Testing labs can verify both identity through mass spectrometry and purity through HPLC analysis

Goicoechea, L., Conde de la Rosa, L., Torres, S., Garcia-Ruiz, C

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Kaushik AK, DeBerardinis RJ