When side effects require medical attention Serious health problems are rare, but they do happen
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With a few exceptions (for example, NCL), the 20-mer LNA ASO typically gave higher enrichment factors than the analog MOE ASO (Fig
Off-label use, misuse, patient expectations: As public demand surges, there is risk of overpromising, misuse (e.g
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Cheng C, Liu Y, Sun L et al (2025) Integrative metabolomics and genomics reveal molecular signatures for type 2 diabetes and its cardiovascular complications