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Classification Nevi can be classified in various ways, according to several factors that are not mutually exclusive: Clinical history: Congenital: present at birth or develop within the 1st 4 weeks of life, though some sources include nevi that appear up to 2 years after birth Acquired: present later in life Location or depth of lesion: Epidermal: located in the epidermis Epidermis The external, nonvascular layer of the skin