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Nucleic Acids Res 38:48074820

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While the existing literature often addresses general dietary recommendations, few reviews integrate molecular mechanisms, population-level data, and interventional evidence linking nutrition with thyroid autoimmunity and cardiovascular risk

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In another study, researchers discovered that tirzepatide treatment, when combined with a decrease in circulating levels of branched-chain amino (BCAA) and keto (BCKA) acid metabolites linked to the development of systemic insulin resistance (IR) and T2DM improves insulin sensitivity in obese mice and humans with T2DM [82]