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Additionally, qPCR confirmed EPPH reduced Bax and Caspase9 mRNA levels, while immunoblotting showed decreased phosphorylation of TP53 and CHK2

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Lichtenstein M, Keini G, Cedar H, Bergman Y (1994)

The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study

The risk profiles

Kranti were collected from agricultural farm of the university, sterilized with 0.1% sodium hypochlorite solution following repeated washing and germinated on Petri plates in seed germinator (BTR Kolkata, LAB-X)