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Older adults are more likely to be on multiple medications, increasing the potential for interactions

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Self-pay and cash-pay patients For patients without insurance coverage or who choose to pay out of pocket, the billing complexity drops dramatically

A 2021 systematic review of 16 randomized controlled trials and 6,276 participants (Markun and colleagues, Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue, Nutrients, 2021) found that B12 supplementation does not reliably reduce fatigue in people who are not deficient