Additionally, to reduce the number of steps and time needed to perform separate reduction and derivatization, an additional experiment based on simultaneous reduction and derivatization reactions of the thiol of interest was carried out (Fig
The compound was dissolved in dry CH 2 Cl 2 under an N 2 atmosphere and reacted with 4-nitrophenyl chloroformate (1.2 equivalents) for 4 h
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4.2 SGLT2 inhibitors in the central nervous system SGLT1 is localized in the pyramidal cells of the brain cortex, Purkinje cerebellum cells, hippocampus pyramidal, and granular cells (Pawlos et al., 2021)
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