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The satiety produced by amylin analogues tends to reduce caloric intake without the extreme food aversion that sometimes occurs with high-dose GLP-1 agonists, which can lead to inadequate protein intake and subsequent muscle loss

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doi: 10.2337/DIABETES.51.2007.S134 20 BorgMJBoundMGrivellJSunZJonesKLHorowitzMet al

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Initially, Notch signaling mediates the dedifferentiation of BECs into LPCs, establishing a progenitor pool essential for initiating regeneration under severe hepatic stress

Patients are advised to report any persistent or severe side effects to their healthcare provider promptly