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Introduction of REW into human IgG1, specific for the hapten 4-hydroxy-3-iodo-5-nitropenylacetyl (NIP), did not reduce production rate, as the amounts of secreted protein were equal to that of wild-type (WT) IgG1 in a serum-free Expi293 expression system (Fig

Thus, recombinant long-acting GLP-1 receptor agonists (RAs) have been developed for the treatment of type 2 diabetes mellitus (T2DM) 24,25 , and were also recently approved to treat obesity 26,27

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