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But heres the thing: As you age, your bodys ability to produce glutathione decreases, leaving you more vulnerable to a slew of diseases and health issues (2)

Jia ML, Wu M, Zhang L, Zhang X, Zhai Q, Jiang T, et al

So, Ravi, maybe switching to you

Our findings demonstrate that Ssu72 directly interacts with GSK3 and induces the dephosphorylation of its inhibitory Ser9 site, thereby enhancing GSK3 activity and ultimately promoting obesogenic adipogenesis via GSK3/-catenin axis

Cell and Developmental Biology 22 , 623650 (2006)

Nevertheless, DPP4 inhibition results in marked reduction of circulating GLP-1 [936], and little data exist surrounding the biological implications of reducing GLP-1 [936] to very low or undetectable levels in vivo