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Using the efficacy estimand model: HbA1c reductions: 3 mg: 1.3% 12 mg: 1.6% 36 mg: 1.5% Placebo: 0.1% 3 mg: 1.3% 12 mg: 1.6% 36 mg: 1.5% Placebo: 0.1% Notably, over 65% of patients in the 36 mg group achieved HbA1c 6.5%

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