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To obtain full blockade of the somatostatin receptor subtypes expressed in the pancreatic islets, we used a cocktail of somatostatin receptor antagonists PRL2915 and PRL3195, which are inhibitors of somatostatin receptor (SSTR)2, SSTR3 and SSTR5 [26, 27]

[1] The IonescuFrohman work then characterized the important finding that pulsatility is preserved under sustained stimulation

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It works even better than allopurinol (0.77 M), the standard gout medication [1]

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