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Meanwhile, human clinical trials continue to show strong safety and benefit profiles

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The SCN, located above the optic nerve crossing, plays a pivotal role in regulating the timing of sleep and wakefulness [174]

doi: 10.1046/j.1440-1789.2000.00268.x 392 YamamotoM.KimM.ImaiH.ItakuraY.OhtsukiG