These medications, which include semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), act like the bodys own GLP-1 hormone, but in doses much larger than the body produces, to regulate insulin and blood sugar, decrease appetite, and slow down stomach emptying
A potential link between disruption of the circadian rhythm and viral infections suppressing the immune system has been suggested by several investigators (113, 115, 134, 135)
Pluquet et al
doi: 10.1007/s10103-012-1102-7
A more recent meta-analysis found higher medial-frontal Glx (glutamate + glutamine) levels in high-risk subjects [39]
doi: 10.3389/frdem.2026.1745504 Received 13 November 2025 Revised 21 December 2025 Accepted 16 January 2026 Published 04 February 2026 Volume 5 - 2026 Edited by Matea Nikolac Perkovi, Rudjer Boskovic Institute, Croatia Reviewed by Xifeng Wang, First Affiliated Hospital of Nanchang University, China Paolo Abondio, IRCCS Institute of Neurological Sciences of Bologna (ISNB), Italy Updates Copyright 2026 Perezcano and Prez-Coria