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doi: 10.1136/bmjnph-2020-000085 31 CallawayE.LedfordH

doi: 10.3389/fmicb.2025.1710051 Received 23 September 2025 Accepted 23 October 2025 Published 06 November 2025 Volume 16 - 2025 Edited by Jianan Zhao, Temple University, United States Reviewed by Jian-Zheng Yang, Southern Medical University, China

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The sponsor described the safety profile as comparable with the broader GLP-1 receptor agonist class

Why CJC-1295/Ipamorelin instead of older GH-releasing peptides: The dual-pathway mechanism produces more consistent IGF-1 elevation and longer-lasting GH pulses than single-pathway alternatives like Sermorelin

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