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The now-elevated calcium levels promote exocytosis of GLP-1containing vesicles, releasing GLP-1 into the circulation

Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency

Because the side effects that you mentioned are pretty serious

Promisingly, the risk conferred is smaller in younger children, and few patients discontinue treatment because of serious adverse effects, supporting the safety of these medications

P: Parnate, 2.7 mg/kg, CRFTM by oral gavage and VP by intraperitoneal injection once a week for 6 weeks in mice at about 8 weeks of age