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Other situations requiring prompt communication with your provider include persistent nausea or vomiting lasting more than 24-48 hours, signs of dehydration (decreased urination, dizziness, dry mouth), visual changes, symptoms of hypoglycemia (shakiness, confusion, rapid heartbeat), or unexplained neck mass or hoarseness

[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Li Y., Lv X., Jiang M., Jin Z

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This invasion is the result of molecular signaling pathways such as epithelial-mesenchymal transition (EMT), which can promote tumor aggressiveness and enable it to spread in distant tissues [216]