Among those who received semaglutide 0.4 mg, metabolic syndrome was reduced from 50.0% at baseline to 25.6% at week 28 in the high baseline ALT subgroup, with a similar decline in the normal ALT subgroup
McKisic, M
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or a post-market analysis of all GLP-1 RA drugs. Commenting on the study, Graham McGeown, honorary professor of physiology at Queens University Belfast, said: [These results do] suggest an association between semaglutide treatment and one form of sight-threatening optic neuropathy, but this would ideally be tested in larger studies
Decreases in hsCRP have also been observed with other classes of antihyperglycemic drug (metformin, dipeptidyl peptidase-4 inhibitors, and SGLT-2 inhibitors), but with less consistency than with GLP-1RAs [27]