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The functional consequence in vitro is that IGF-1 LR3 produces sustained IGF-1R/IRS-1/PI3K/Akt/mTORC1 signalling without being rapidly quenched by secreted IGFBPs in conditioned medium
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[DOI] [PMC free article] [PubMed] [Google Scholar] 101.Sajjad H., Majeed M., Imtiaz S., Siddiqah M., Sajjad A., Din M., Ali M
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