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No Rebound Hunger or Metabolic Adaptation Appetite suppressants that work through central mechanisms (GLP-1 agonists, sympathomimetics, serotonergic agents) typically create tolerance over time, requiring dose escalation, and often produce rebound hunger when discontinued

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However, its clinical application must be approached with a critical and nuanced understanding of the current evidence gap

Acute diarrhea in dogs: current management and potential role of dietary polyphenols supplementation

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I think that the safety profiles are showing that, but again, God forbid you have something growing that you dont know about yet, and you stimulate that, that would stink