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Deacon, Johnsen, Holst)

Therapies for inter-relating diabetes and obesity GLP-1 and obesity

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Designing small molecules able to target multiple receptors might sound difficult, but Septerna says the allosteric binding site it has discovered is even better conserved across all incretin receptors than the site targeted by peptides and other small molecule drugs

Funciones principales de la GLP-1 en el organismo La GLP-1 ejerce mltiples efectos fisiolgicos que van ms all del control glucmico, actuando como un regulador metablico integral