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We hypothesize that GE2 treatment will mitigate the cognitive and inflammatory impacts of a WD and enhance cognition, reduce inflammation, and increase neuroplasticity in limbic regions of the brain in middle-aged male and female rats

Is insulin-dependent diabetes mellitus caused by coxsackievirus B infection

Intracellular ROS readily oxidize PUFA, leading to the formation of lipid peroxides that strongly promote the initiation of ferroptosis (Doll and Conrad, 2017)

Acetyl L-Carnitine (ALC) is a highly bioavailable form of L-carnitine that crosses the blood-brain barrier to support cognitive function, neurological health, mood balance, and energy production.* ALC promotes mitochondrial function, neurotransmitter synthesis, and antioxidant activity, making it a valuable tool for supporting brain health, nerve comfort, and overall metabolic vitality.* The acetyl derivative of L-carnitine, acetyl-L-carnitine is involved in the metabolism of protein, carbohydrates and fats, as well as the conversion of fats into energy.* Carnitine shuttles fats (triglycerides) into the mitochondria so these fats can be used for fuel.* Acetyl-L-carnitine crosses the blood brain barrier more readily than L-carnitine

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Weisman A, Fazli GS, Johns A, Booth G: Evolving trends in the epidemiology, risk factors, and prevention of type 2 diabetes: A review