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For LFC, significant reductions were observed in individuals with MAFLD (Class IV

They should be considered superior in most patients, including those with HF and CKD.3 However, ischaemia prevention is superior for GLP-1 RAs, thus making them preferable in patients with predominant ASCVD risk.3 Differences in routes of administration and adverse effect profiles may also play a role in prescription decisions

They also had lower levels of inflammation and oxidative stress

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Call 999 or go to your nearest A&E immediately if you experience: Signs of a serious allergic reaction (anaphylaxis) , including facial or throat swelling, difficulty breathing, a rapid heartbeat, or a widespread rash this is a medical emergency Severe difficulty breathing or collapse Contact your GP, NHS 111, or your trial medical team promptly if you experience: Persistent or severe vomiting or diarrhoea that prevents adequate fluid or food intake