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In mammals, the GPxs family consists of eight members (GPx1-GPx8) identified so far

(3) Fan Ye, Sunita Mathur, Min Liu, Stephen E Borst, et al (2016) Overexpression of IGF-1 attenuates skeletal muscle damage and accelerates muscle regeneration and functional recovery after disuse Experimental Physiology, 2013 Jan 4, Volume 98 (Issue 5), Pages 10381052

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In contrast, GLP-1RAs exert antiatherogenic and anti-inflammatory effects that promote plaque stabilization and reduce major adverse cardiovascular events (MACE), with the most pronounced effect on ischemic stroke [5, 15, 22, 24]