In WT and obese animals, AOD9604 reduces fat mass, increases 3-AR expression, enhances lipolysis, and stimulates energy expenditure and fat oxidation
But its edge may not last long
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Prolonged, excessive GH exposure can, in principle, produce features associated with GH excesssoft-tissue overgrowth, joint problems, cardiac strain, and metabolic disturbance
On the other hand, it has been illustrated that homocysteine reduction could have favorable effects on migraine disability, severity, and frequency of attacks (54)
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