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Side effects to expect during the transition Because your body has already adapted to GLP-1 receptor stimulation from tirzepatide, the transition to semaglutide is generally well tolerated

What blood sugar changes should I expect if I'm on both medications

Each medication can affect people differently, so it's important to monitor your sleep

Nausea Diarrhea Vomiting Constipation Abdominal discomfort These effects are most likely to occur when increasing dosages, and often improve over time as the body adjusts

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