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For this reason, using oral semaglutide with other prescription weight loss medications is generally not recommended unless you are under close medical supervision

Developed by Eli Lilly, retatrutide simultaneously targets GLP-1, GIP, and glucagon receptors a mechanism that sets it apart from currently approved medicines such as semaglutide and tirzepatide

Pretty happy so far

With more food sitting in the stomach for longer, there is more stomach acid that can reflux and shoot back up into the esophagus

What experts say about using GLP-1 medication for weight loss Only two anti-diabetic medications are FDA-approved for weight management in people who do not have diabetes: semaglutide (Wegovy) and liraglutide (Saxenda)

While semaglutide works by activating the GLP-1 receptor, retatrutide activates GLP-1, GIP, and GCG receptors, which may offer even more benefits