and vascularity should be preserved
Subsequent STEP trials (2 through 8) have replicated the effect across different populations and dosing schedules
Beef, chicken, eggs, oatmeal and lentils are some of the best sources
As of July 1, 2024, there are a number of medications removed from Highmark Formularies & some remaining, that now have Step Therapy requirements
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Currently, the effects of 2.4 mg semaglutide once weekly are being explored in 1200 participants with biopsy-confirmed NASH in a Phase III clinical trial with a combined primary endpoint of resolution of NASH without worsening fibrosis, improvement in liver fibrosis without worsening of steatohepatitis, and time to first liver-related clinical event (NCT04822181) (see Table 2)