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Despite some conflicting results obtained in knockout animals, it is clear that the H3R plays an important role in regulating food intake, and its activation is generally orexigenic

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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Wiegand U.W., Chou R.C., Maulik D., Levy G

Patients who have undergone bariatric surgery may be at increased risk of dehydration and electrolyte disturbances when experiencing GLP-1 receptor agonist-related gastrointestinal side effects, particularly if vomiting is severe