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"This work not only highlights the potential off-target effect of semaglutide as an effective drug to treat metabolic osteoarthritis," the team from China and the US writes in their published paper, "but also reveals a weight loss-independent repair mechanism." In addition to mouse experiments, the researchers also conducted a randomized human trial to assess the effects of semaglutide on pain, mobility, and tissue degradation in individuals with osteoarthritis and obesity

As hormone levels fluctuate, collagen production often declines, leading to a loss of firmness and elasticity

Physiol Behav 2012

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The differences between LC and control groups in the studied parameters at either Day 0 or Day 8 were analyzed using the student t-test

Quick Answer: Most research and clinical observations suggest that it is generally safe to take inositol with semaglutide, provided you are monitored by a healthcare professional