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Environ Health
Advances in Nutrition, 15 (8), 100273
GPX4s catalytic activity depends on a key triad structure consisting of selenocysteine at position 46, aspartic acid at position 81, and tryptophan at position 136 [55]
Simultaneously, it regulates the activity of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), enabling a controlled remodeling of the extracellular matrix
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