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In a separate 36-week phase 2 trial in 281 T2D patients treated with up to 12mg retatrutide weekly, researchers observed significant reductions in HbA1c

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That guideline reinforces the need to treat GLP-1 medicine use as part of broader professional care

It is also important to consider that long-term use of GLP-1R agonists may have adverse effects on muscle mass, composition, and function, and that many patients with ASUDs already have nutritional problems and/or sarcopenia [104]

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