Recent trials have shown: Up to 20% body weight reduction with weekly GLP-1 agonists (Wilding et al., NEJM) Improvements in HbA1c, fasting glucose, and cardiovascular outcomes (Marso et al., NEJM) This drug class is now widely used for: Obesity (with or without diabetes) Type 2 diabetes PCOS-related insulin resistance Metabolic syndrome Common Side Effects and Patient Concerns Despite their benefits, GLP-1 agonists are not without risks or drawbacks
Protein-Rich Foods: Eggs Chicken, turkey, or fish (like salmon) Beans and lentils Why It Works : Protein helps release GLP-1, so you feel fuller longer and your blood sugar stays in a healthy range
5 GLP-1 Agonists Side Effects Its important to note that taking GLP-1 agonists can cause several unwanted effects depending on how your body responds to the hormone
These pathways are often reviewed in laboratory models involving metabolic signalling, receptor interaction, glucose response, energy balance and appetite-related signalling
It is not a drug
However, a long-term exploratory RCT in 150 people with obesity found that differences in eating disorders psychopathology scores were not maintained at 52 weeks when liraglutide in combination with behavioral therapy was compared with behavioral therapy alone 215
