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74 Besides the expected improvements in metabolism and hepatic steatosis, liver fibrosis markers, including the fibrosis-4 index, ferritin, and type IV collagen 7s, were observed to decrease after 24 weeks of treatment

Important aspects like fibroblast heterogeneity, functional specialization and cellular plasticity are also discussed as well as the implications that these aspects may have in disease and in the design of novel therapeutics

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