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The American Diabetes Association recommends at least 150 minutes of moderate-intensity aerobic activity weekly, plus resistance training 2-3 times per week as tolerated, adjusted based on individual capacity and medical status

This means ~90% savings for patients who cannot afford the branded drug

However, nausea and digestive discomfort appeared more often among people taking GLP-1 drugs, and some participants discontinued treatment because of these side effects

Thyroxine replacement increases central 5-hydroxytryptamine activity and reduces depressive symptoms in hypothyroidism

The clinical outcomes of interest were QALYs and life-years

Tirzepatide is a dual GIP + GLP-1 agonist