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Rationale for GLP-1/Glucagon Combination Therapy for Weight Loss Although significant progress was made in understanding the potential use of the endogenous GLP-1/glucagon co-agonist OXM as a weight loss therapeutic in the early 2000s, evidence from various pre-clinical and human studies prior to this demonstrated the distinct mechanisms of weight loss afforded by these hormones

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[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Raub A et al

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Studies in PCa suggest that arginine derived metabolites promote tumor proliferation by suppressing apoptosis through redox modulation (49)